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Tg(Myh6-MYL3*A57G)#Dsc
Transgene Detail
Nomenclature
Symbol: Tg(Myh6-MYL3*A57G)#Dsc
Name: transgene insertion, Danuta Szczesna-Cordary
MGI ID: MGI:5909257
Synonyms: Tg-A57G
Transgene: Tg(Myh6-MYL3*A57G)#Dsc  Location: unknown  
Transgene
origin
Strain of Origin:  Not Specified
Transgene
description
Transgene Type:    Transgenic (Humanized sequence, Inserted expressed sequence)
Mutation:    Insertion
 
Tg(Myh6-MYL3*A57G)#Dsc expresses 1 gene
 
Mutation detailsThe human ventricular essential light chain cDNA with an alanine to glycine mutation at residue 57 (A57G) is under the control of the mouse alpha-myosin heavy chain promoter. Lines L1, L5, and L2 were generated, however the pound symbol (#) is used when line is not specified and/or lines are pooled. (J:178377)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:178377 Muthu P, et al., Structural and functional aspects of the myosin essential light chain in cardiac muscle contraction. FASEB J. 2011 Dec;25(12):4394-405
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
12/11/2018
MGI 6.13
The Jackson Laboratory