Ago2^tm1.2Tara
Targeted Allele Detail

Summary

• Symbol: Ago2^tm1.2Tara
• Name: argonaute RISC catalytic subunit 2; targeted mutation 1.2, Alexander Tarakhovsky
• MGI ID: MGI:5908164
• Gene: Ago2 Location: Chr15:72967693-73056777 bp, - strand Genetic Position: Chr15, 33.92 cM
• Alliance: Ago2^tm1.2Tara page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:243335
• Parent Cell Line: E14.1 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: An FRT-flanked neo cassette with a loxP site was inserted downstream of exon 11 and an additional loxP site was inserted btween exon 8 and 9. Flp-mediated recombination removed the neo cassette leaving exons 9 through 11 floxed. Cre-mediated recombination removed exons 9 through 11. (J:243335)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ago2 Mutation: 56 strains or lines available

References

• Original: J:243335 Tang F, et al., mRNA-Seq whole-transcriptome analysis of a single cell. Nat Methods. 2009 May;6(5):377-82
• All: 1 reference(s)