Pjvk^tm2.1Ugds
Targeted Allele Detail

Summary

• Symbol: Pjvk^tm2.1Ugds
• Name: pejvakin; targeted mutation 2.1, Unite de Genetique des Deficits Sensoriels
• MGI ID: MGI:5908028
• Gene: Pjvk Location: Chr2:76480617-76488898 bp, + strand Genetic Position: Chr2, 45.08 cM
• Alliance: Pjvk^tm2.1Ugds page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:228036
• Parent Cell Line: CK35 (ES Cell)
• Strain of Origin: 129S2/SvPas

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A loxP site was inserted in intron 1 and a floxed pgk-neo cassette was inserted in intron 2 via homologous recombination. Cre mediated recombination removed exon 2 and the neo cassette. (J:228036)

Expression

In Mice Carrying this Mutation:

1 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Pjvk Mutation: 19 strains or lines available

References

• Original: J:228036 Delmaghani S, et al., Hypervulnerability to Sound Exposure through Impaired Adaptive Proliferation of Peroxisomes. Cell. 2015 Nov 5;163(4):894-906
• All: 2 reference(s)