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Targeted Allele Detail
Symbol: Il17ratm2.1Koll
Name: interleukin 17 receptor A; targeted mutation 2.1, Jay K Kolls
MGI ID: MGI:5907986
Synonyms: Il17rafl
Gene: Il17ra  Location: Chr6:120463181-120483731 bp, + strand  Genetic Position: Chr6, 56.95 cM
Germline Transmission:  Earliest citation of germline transmission: J:101977
Parent Cell Line:  Bruce 4 (ES Cell)
Strain of Origin:  B6.Cg-Thy1a
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
Mutation detailsA loxP site was inserted upstream of exon 2. An FRT-flanked neomycin resistance cassette with a 3' loxP site was inserted upstream of exon 4. Flp-mediated recombination removed the FRT-flanked neo cassette. (J:237978)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Il17ra Mutation:  4 strains or lines available
Original:  J:237978 Kumar P, et al., Intestinal Interleukin-17 Receptor Signaling Mediates Reciprocal Control of the Gut Microbiota and Autoimmune Inflammation. Immunity. 2016 Mar 15;44(3):659-71
All:  6 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.15
The Jackson Laboratory