Psmd14^tm1.1Yzli
Targeted Allele Detail

Summary

• Symbol: Psmd14^tm1.1Yzli
• Name: proteasome (prosome, macropain) 26S subunit, non-ATPase, 14; targeted mutation 1.1, Yongzhong Liu
• MGI ID: MGI:5907976
• Synonyms: Poh1^f
• Gene: Psmd14 Location: Chr2:61542038-61630720 bp, + strand Genetic Position: Chr2, 35.56 cM
• Alliance: Psmd14^tm1.1Yzli page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:227910
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: A loxP site was inserted upstream of exon 6 and a loxP site and FRT flanked neo cassette were inserted downstream of exon 6 via homologous recombination. Flp mediated recombination removed the neo cassette. (J:227910)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Psmd14 Mutation: 51 strains or lines available

References

• Original: J:227910 Wang B, et al., POH1 deubiquitylates and stabilizes E2F1 to promote tumour formation. Nat Commun. 2015;6:8704
• All: 4 reference(s)