Dll1^{tm5.1(Dll1)Kag}
Targeted Allele Detail

Summary

• Symbol: Dll1^{tm5.1(Dll1)Kag}
• Name: delta like canonical Notch ligand 1; targeted mutation 5.1, Ryoichiro Kageyama
• MGI ID: MGI:5907606
• Synonyms: Dll1 type 2 mutant
• Gene: Dll1 Location: Chr17:15587616-15597134 bp, - strand Genetic Position: Chr17, 8.95 cM
• Alliance: Dll1^{tm5.1(Dll1)Kag} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:227685
• Parent Cell Line: TT2 (ES Cell)
• Strain of Origin: (C57BL/6NCrlj x CBA/JNCrlj)F1

Mutation description

• Allele Type: Targeted (Inserted expressed sequence, Reporter)
• Mutations: Insertion, Intragenic deletion
• Dll1^{tm5.1(Dll1)Kag} expresses 1 gene
  Knock-in expresses:
  

  Organism	Expressed Gene	Note
  Not Specified	Dll1

• Mutation details: The coding region of the first exon was replaced with a Dll1 cDNA fused with luciferase and an FRT flanked neo cassette via homologous recombination. Flp mediated recombination removed the neo cassette. (J:227685)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Dll1 Mutation: 46 strains or lines available

References

• Original: J:227685 Shimojo H, et al., Oscillatory control of Delta-like1 in cell interactions regulates dynamic gene expression and tissue morphogenesis. Genes Dev. 2016 Jan 1;30(1):102-16
• All: 3 reference(s)