Gt(ROSA)26Sor^{tm1(CAG-Mlip)Dzw}
Targeted Allele Detail

Summary

• Symbol: Gt(ROSA)26Sor^{tm1(CAG-Mlip)Dzw}
• Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 1, Da-Zhi Wang
• MGI ID: MGI:5907349
• Synonyms: CIP^KI, Rosa-CIP
• Gene: Gt(ROSA)26Sor Location: Chr6:113044389-113054205 bp, - strand Genetic Position: Chr6, 52.73 cM
• Alliance: Gt(ROSA)26Sor^{tm1(CAG-Mlip)Dzw} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:227485
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, Epitope tag, Inserted expressed sequence)
• Mutation: Insertion
• Mutation details: A construct consisting of a splice acceptor site, CAG promoter, floxed-neo-stop cassette, and flag-tagged Milp was inserted in intron 1 via homologous recombination. (J:227485)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gt(ROSA)26Sor Mutation: 944 strains or lines available

References

• Original: J:227485 Huang ZP, et al., Cardiomyocyte-enriched protein CIP protects against pathophysiological stresses and regulates cardiac homeostasis. J Clin Invest. 2015 Nov 2;125(11):4122-34
• All: 2 reference(s)