About   Help   FAQ
Tg(Myh6-LMNA*E82K)35Lizh
Transgene Detail
Nomenclature
Symbol: Tg(Myh6-LMNA*E82K)35Lizh
Name: transgene insertion 35, Lianfeng Zhang
MGI ID: MGI:5907285
Synonyms: LmnaE82K
Transgene: Tg(Myh6-LMNA*E82K)35Lizh  Location: unknown  
Transgene
origin
Strain of Origin:  Not Specified
Transgene
description
Transgene Type:    Transgenic (Humanized sequence, Inserted expressed sequence)
Mutation:    Insertion
 
Tg(Myh6-LMNA*E82K)35Lizh expresses 1 gene
 
Mutation detailsThe human gene with a G to A substitution resulting in the E82K mutation is under the cardiac-specific alpha-MHC promoter. Line 30 and 35 were analyzed. (J:167734)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Disease models
Loading...
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:167734 Lu D, et al., LMNA E82K mutation activates FAS and mitochondrial pathways of apoptosis in heart tissue specific transgenic mice. PLoS One. 2010;5(12):e15167
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
02/23/2021
MGI 6.16
The Jackson Laboratory