Txn1^tm1.1Ees
Targeted Allele Detail

Summary

• Symbol: Txn1^tm1.1Ees
• Name: thioredoxin 1; targeted mutation 1.1,Edward E Schmidt
• MGI ID: MGI:5902508
• Synonyms: Txn1^cond, Txn1^fl
• Gene: Txn1 Location: Chr4:57943373-57956411 bp, - strand Genetic Position: Chr4, 31.87 cM
• Alliance: Txn1^tm1.1Ees page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:101977
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: (C57BL/6 x 129S6/SvEvTac)F1

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: The targeting vector is designed to insert a loxP site in intron 1, an FRT-flanked self-excising FLPe/neo cassette (frt::Prm1-FLPe-SV40pA::Pol2-neo-SV40pA::frt) in intron 2, and a second loxP site in intron 3 of the the gene. The neo cassette was deleted by transiently transfection of an expression vector of flp recombinase in the ES cells. (J:101977)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Txn1 Mutation: 20 strains or lines available

References

• Original: J:101977 The Jackson Laboratory, Information obtained from The Jackson Laboratory, Bar Harbor, ME. Unpublished. 2005-2017
• All: 4 reference(s)