Igs18^tm1.1Nju
Targeted Allele Detail

Summary

• Symbol: Igs18^tm1.1Nju
• Name: intergenic site 18; targeted mutation 1.1, Model Animal Research Center for Nanjing University
• MGI ID: MGI:5902163
• Gene: Igs18 Location: unknown Genetic Position: ChrX, Syntenic
• Alliance: Igs18^tm1.1Nju page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:240206
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129S6/SvEvTac

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: A loxP site flanked neomycin resistance gene cassette was inserted downstream of Magea1. The neo cassette was removed through subsequent cre-mediated recombination. This allele was used together with the Igs19^tm1Nju allele to create the Del(XMagea1-Magea6)1Nju allele. (J:240206)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Igs18 Mutation: 0 strains or lines available

References

• Original: J:240206 Hou S, et al., The Magea gene cluster regulates male germ cell apoptosis without affecting the fertility in mice. Sci Rep. 2016 May 26;6:26735
• All: 1 reference(s)