Fstl3^tm1.2Sjl
Targeted Allele Detail

Summary

• Symbol: Fstl3^tm1.2Sjl
• Name: follistatin-like 3; targeted mutation 1.2, Sejin Lee
• MGI ID: MGI:5901941
• Gene: Fstl3 Location: Chr10:79613108-79618464 bp, + strand Genetic Position: Chr10, 39.72 cM, cytoband C1
• Alliance: Fstl3^tm1.2Sjl page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:182827
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: A loxP site was inserted upstream of exon 3 and a floxed neo cassette was inserted downstream of exon 5 via homologous recombination. Cre mediated recombination deleted the loxP-flanked neo cassette yielding this allele with loxP sites flanking exons 3-5. (J:182827)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Fstl3 Mutation: 22 strains or lines available

References

• Original: J:182827 Lee SJ, et al., Regulation of muscle mass by follistatin and activins. Mol Endocrinol. 2010 Oct;24(10):1998-2008
• All: 1 reference(s)