Tg(CAG-ARL13B/mCherry/GECO1.2)1Clph
Transgene Detail

Summary

• Symbol: Tg(CAG-ARL13B/mCherry/GECO1.2)1Clph
• Name: transgene insertion 1, David E Clapham
• MGI ID: MGI:5898420
• Synonyms: Arl13b-mCHerry-GECO1.2^tg
• Transgene: Tg(CAG-ARL13B/mCherry/GECO1.2)1Clph Location: unknown Genetic Position: Chr1, Syntenic
• Alliance: Tg(CAG-ARL13B/mCherry/GECO1.2)1Clph page

Transgene origin

• Strain of Origin: C57BL/6J

Transgene description

• Transgene Type: Transgenic (Humanized sequence, Reporter)
• Mutation: Insertion
• Mutation details: The CAG promoter drives expression of full-length human ARL13B (ADP-ribosylation factor-like 13B)fused to mCherry and GECO1.2. The GECO1.2 component is an improved green fluorescent GECI (genetically encoded calcium indicator) with an apparent K>d< of 450 nm. A single copy of the transgene integrated in a non-coding region of mouse Chromosome 1 (position 174,611,546). (J:232710)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:232710 Delling M, et al., Primary cilia are not calcium-responsive mechanosensors. Nature. 2016 Mar 31;531(7596):656-60
• All: 1 reference(s)