Mir743tm1Wtsi
Targeted Allele Detail
|
Symbol: |
Mir743tm1Wtsi |
Name: |
microRNA 743; targeted mutation 1, Wellcome Trust Sanger Institute |
MGI ID: |
MGI:5898146 |
Synonyms: |
Mir743tm1(mirKO)Wtsi |
Gene: |
Mir743 Location: ChrX:65820363-65820424 bp, - strand Genetic Position: ChrX, 34.81 cM
|
|
Mutant Cell Lines: |
mirKO_ES_PuDtk_28E1, mirKO_ES_PuDtk_28E2, mirKO_ES_PuDtk_28E3, mirKO_ES_PuDtk_28E4, mirKO_ES_PuDtk_28E5, mirKO_ES_PuDtk_28E6, mirKO_ES_PuDtk_28E7 |
Germline Transmission: |
Unknown
|
Parent Cell Line: |
JM8A3 (ES Cell)
|
Strain of Origin: |
C57BL/6N-Atm1Brd
|
Project Collection: |
Sanger miRNA knockouts
|
|
Allele Type: |
|
Targeted (Null/knockout) |
Mutations: |
|
Insertion, Intragenic deletion
|
|
|
Mutation details: The insertion of the PGK_EM7_PuDtk_bGHpA cassette created a deletion starting at position 63037601 and ending at position 63037328 of Chromosome X (Genome Build 38). This deletion eliminates the DNA sequence for this microRNA. The cassette is composed of a loxP site followed by an F3 site followed by a PGK-puromycin-delta-tk cassette, a loxP site and an FRT site.
(J:174268)
|
|
|
Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
|
Carrying any Mir743 Mutation: |
1 strain or line available
|
|
Original: |
J:174268 Prosser HM, et al., A resource of vectors and ES cells for targeted deletion of microRNAs in mice. Nat Biotechnol. 2011 Aug 7;29(9):840-5 |
All: |
1 reference(s) |
|