Il33^tm1.1Bryc
Targeted Allele Detail

Summary

• Symbol: Il33^tm1.1Bryc
• Name: interleukin 33; targeted mutation 1.1, Paul Bryce
• MGI ID: MGI:5897873
• Synonyms: IL33^fl
• Gene: Il33 Location: Chr19:29902514-29938118 bp, + strand Genetic Position: Chr19, 24.56 cM, cytoband C2
• Alliance: Il33^tm1.1Bryc page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:101977
• Parent Cell Line: iTL IC1 (ES Cell)
• Strain of Origin: C57BL/6NTac

Mutation description

• Allele Type: Targeted (Conditional ready, Reporter)
• Mutation: Insertion
• Mutation details: The targeting vector is designed to insert a loxP site upstream of exon 5, and an FRT-flanked and loxP-flanked neomycin resistance (neo) cassette downstream of exon 7 of the gene. An internal ribosome entry site (IRES) fused to an enhanced green fluorescent protein sequence was inserted into the 3 prime UTR. Flp-mediated recombination removed the FRT-flanked neo cassette leaving exons 5 through 7 floxed. (J:101977)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Il33 Mutation: 32 strains or lines available

References

• Original: J:101977 The Jackson Laboratory, Information obtained from The Jackson Laboratory, Bar Harbor, ME. Unpublished. 2005-2017
• All: 30 reference(s)