Tmem258tm1.1(KOMP)Vlcg
Targeted Allele Detail
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Symbol: |
Tmem258tm1.1(KOMP)Vlcg |
Name: |
transmembrane protein 258; targeted mutation 1.1, Velocigene |
MGI ID: |
MGI:5892142 |
Synonyms: |
Tmem258- |
Gene: |
Tmem258 Location: Chr19:10181566-10185188 bp, + strand Genetic Position: Chr19, 6.54 cM
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Alliance: |
Tmem258tm1.1(KOMP)Vlcg page
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IMPC: |
Tmem258 gene page |
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Mutant Cell Line: |
19703A-G5 |
Germline Transmission: |
Earliest citation of germline transmission:
J:240635
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Parent Cell Line: |
VGB6 (ES Cell)
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Strain of Origin: |
C57BL/6NTac
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Project Collection: |
KOMP-Regeneron
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Allele Type: |
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Targeted (Null/knockout, Reporter) |
Mutations: |
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Insertion, Intragenic deletion
Vector: ZEN-Ub1
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Mutation details: The insertion of Velocigene cassette ZEN-Ub1 created a deletion of size 3026bp between positions 10278755-10281780 of Chromosome 19 (Genome Build37). Exons 2 and 3 were replaced with a lacZ gene and a loxP-flanked neomycin selection cassette. The loxP-flanked cassette was removed by cre-mediated recombination.
(J:240635)
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Tmem258 Mutation: |
13 strains or lines available
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Original: |
J:240635 Graham DB, et al., TMEM258 Is a Component of the Oligosaccharyltransferase Complex Controlling ER Stress and Intestinal Inflammation. Cell Rep. 2016 Dec 13;17(11):2955-2965 |
All: |
1 reference(s) |
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