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Btbd18tm1Dean
Targeted Allele Detail
Nomenclature
Symbol: Btbd18tm1Dean
Name: BTB (POZ) domain containing 18; targeted mutation 1, Jurrien Dean
MGI ID: MGI:5888779
Synonyms: Btbd18Null
Gene: Btbd18  Location: Chr2:84659079-84668780 bp, + strand  Genetic Position: Chr2, 49.45 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:240025
Parent Cell Line:  v6.5 (ES Cell)
Strain of Origin:  (C57BL/6 x 129S4/SvJae)F1
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsExon 5, which contains most of the gene coding sequence, was replaced with a loxP-flanked neomycin selection cassette. (J:240025)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 2 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Btbd18 Mutation:  6 strains or lines available
References
Original:  J:240025 Zhou L, et al., BTBD18 Regulates a Subset of piRNA-Generating Loci through Transcription Elongation in Mice. Dev Cell. 2017 Mar 13;40(5):453-466.e5
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
02/16/2021
MGI 6.16
The Jackson Laboratory