Zdhhc13^tm1.1Jyen
Targeted Allele Detail

Summary

• Symbol: Zdhhc13^tm1.1Jyen
• Name: zinc finger, DHHC domain containing 13; targeted mutation 1.1, Jeffrey Jong-Young Yen
• MGI ID: MGI:5883849
• Synonyms: Zdhhc13^flox
• Gene: Zdhhc13 Location: Chr7:48438751-48477188 bp, + strand Genetic Position: Chr7, 31.11 cM, cytoband B3
• Alliance: Zdhhc13^tm1.1Jyen page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:240181
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A loxP site was inserted into intron 1 and an FRT site flanked neomycin resistance gene cassette and a second loxP site were inserted into intron 2. The neo cassette was removed through subsequent flp-mediated recombination, leaving a conditional-ready allele with exon 2 floxed. (J:240181)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Zdhhc13 Mutation: 31 strains or lines available

References

• Original: J:240181 Chen LY, et al., Protein Palmitoylation by ZDHHC13 Protects Skin against Microbial-Driven Dermatitis. J Invest Dermatol. 2017 Apr;137(4):894-904
• All: 1 reference(s)