Cxxc1tm1.1Liwa
Targeted Allele Detail
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Symbol: |
Cxxc1tm1.1Liwa |
Name: |
CXXC finger protein 1; targeted mutation 1.1, Lie Wang |
MGI ID: |
MGI:5882522 |
Synonyms: |
Cxxc1fl |
Gene: |
Cxxc1 Location: Chr18:74349283-74354564 bp, + strand Genetic Position: Chr18, 50.7 cM
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Alliance: |
Cxxc1tm1.1Liwa page
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Germline Transmission: |
Earliest citation of germline transmission:
J:239921
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Parent Cell Line: |
Not Specified (ES Cell)
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Strain of Origin: |
129
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Allele Type: |
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Targeted (Conditional ready, No functional change) |
Mutation: |
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Insertion
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Mutation details: A loxP site was inserted into intron 3 and an FRT site flanked neomycin resistance gene cassette and a second loxP site into intron 5. Subsequently, the neo cassette was removed through flp-mediated recombination, leaving a conditional-ready allele with exons 4 and 5 floxed.
(J:239921)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Cxxc1 Mutation: |
28 strains or lines available
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Original: |
J:239921 Cao W, et al., CXXC finger protein 1 is critical for T-cell intrathymic development through regulating H3K4 trimethylation. Nat Commun. 2016 May 23;7:11687 |
All: |
8 reference(s) |
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