Bhlha15^tm5Skz
Targeted Allele Detail

Summary

• Symbol: Bhlha15^tm5Skz
• Name: basic helix-loop-helix family, member a15; targeted mutation 5, Stephen F Konieczny
• MGI ID: MGI:5882090
• Synonyms: Mist1^flox
• Gene: Bhlha15 Location: Chr5:144127104-144131259 bp, + strand Genetic Position: Chr5, 83.05 cM, cytoband G2-G3
• Alliance: Bhlha15^tm5Skz page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:239586
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: Exon 2 was flanked by loxP sites and sequence for a biotin tag was inserted at the 5' end of the gene and MYC tag sequence at the 3' end. This creates a conditional-ready allele with exon 2 floxed and codes for a peptide with an N-terminal biotin tag and C-terminal MYC tag. (J:239586)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Bhlha15 Mutation: 14 strains or lines available

References

• Original: J:239586 Lo HG, et al., A single transcription factor is sufficient to induce and maintain secretory cell architecture. Genes Dev. 2017 Jan 15;31(2):154-171
• All: 1 reference(s)