Nkx2-5tm4Mwc
Targeted Allele Detail
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Symbol: |
Nkx2-5tm4Mwc |
Name: |
NK2 homeobox 5; targeted mutation 4, Mauro W Costa |
MGI ID: |
MGI:5828837 |
Synonyms: |
Nkx2-5C |
Gene: |
Nkx2-5 Location: Chr17:27057638-27063962 bp, - strand Genetic Position: Chr17, 13.6 cM
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Alliance: |
Nkx2-5tm4Mwc page
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Germline Transmission: |
Earliest citation of germline transmission:
J:239808
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Parent Cell Line: |
Bruce 4 (ES Cell)
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Strain of Origin: |
B6.Cg-Thy1a
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Allele Type: |
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Targeted (No functional change) |
Mutation: |
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Undefined
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Mutation details: This allele has a loxP-flanked neomycin cassette in the 3-prime UTR, and no other alteration, thereby providing a control allele for point mutations generated from a derivative construct.
(J:239808)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Nkx2-5 Mutation: |
21 strains or lines available
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Original: |
J:239808 Furtado MB, et al., Point mutations in murine Nkx2-5 phenocopy human congenital heart disease and induce pathogenic Wnt signaling. JCI Insight. 2017 Mar 23;2(6):e88271 |
All: |
1 reference(s) |
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