Epc1^{tm1e(EUCOMM)Wtsi}
Targeted Allele Detail

Summary

• Symbol: Epc1^{tm1e(EUCOMM)Wtsi}
• Name: enhancer of polycomb homolog 1; targeted mutation 1e, Wellcome Trust Sanger Institute
• MGI ID: MGI:5828782
• Gene: Epc1 Location: Chr18:6435951-6516108 bp, - strand Genetic Position: Chr18, 4.48 cM, cytoband A1
• Alliance: Epc1^{tm1e(EUCOMM)Wtsi} page
• IMPC: Epc1 gene page

Mutation origin

• Mutant Cell Line: EPD0002_3_G03
• Germline Transmission: Earliest citation of germline transmission: J:82809
• Parent Cell Line: SI2.3 (ES Cell)
• Strain of Origin: 129S7/SvEvBrd-Hprt1^b-m2
• Project Collection: EUCOMM

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutation: Insertion Vector: L1L2_gt0
• Mutation details: This allele resulted from loss of the 3' loxP site from Epc1^{tm1a(EUCOMM)Wtsi}, a "KO first" allele having a frt site-flanked splice acceptor-lacZ/neo-pA cassette followed by a loxP site upstream of exon 2 and a second loxP site downstream of exon 2. The present allele cannot be converted to a conditional allele. (J:173534)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Epc1 Mutation: 55 strains or lines available

References

• Original: J:82809 European Mouse Mutant Archive, Information obtained from the European Mouse Mutant Archive (EMMA). Unpublished. 2003-2013
• All: 3 reference(s)