Prkcg^tm1.1Ddg
Targeted Allele Detail

Summary

• Symbol: Prkcg^tm1.1Ddg
• Name: protein kinase C, gamma; targeted mutation 1.1, David D Ginty
• MGI ID: MGI:5828011
• Synonyms: PKCg^myrGFP
• Gene: Prkcg Location: Chr7:3352038-3379615 bp, + strand Genetic Position: Chr7, 1.93 cM
• Alliance: Prkcg^tm1.1Ddg page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:239228
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129S6/SvEvTac

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutation: Insertion
• Mutation details: A myristoylated GFP (mGFP)-FRT-Neomycin-FRT-loxP cassette was introduced to the first coding ATG of exon 1. Flp-mediated recombination removed the FRT-flanked neo cassette. (J:239228)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Prkcg Mutation: 42 strains or lines available

References

• Original: J:239228 Abraira VE, et al., The Cellular and Synaptic Architecture of the Mechanosensory Dorsal Horn. Cell. 2017 Jan 12;168(1-2):295-310.e19
• All: 2 reference(s)