Sufu^tm1Zyzh
Targeted Allele Detail

Summary

• Symbol: Sufu^tm1Zyzh
• Name: SUFU negative regulator of hedgehog signaling; targeted mutation 1, Zunyi Zhang
• MGI ID: MGI:5825362
• Synonyms: Sufu^fx
• Gene: Sufu Location: Chr19:46385335-46477243 bp, + strand Genetic Position: Chr19, 38.85 cM
• Alliance: Sufu^tm1Zyzh page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:235489
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A loxP site was inserted upstream of exon 7. An FRT-flanked neomycin resistance cassette with a 5' lox P site was inserted downstream of exon 7. (J:235489)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Sufu Mutation: 59 strains or lines available

References

• Original: J:235489 Li J, et al., Suppressor of Fused Is Required for Determining Digit Number and Identity via Gli3/Fgfs/Gremlin. PLoS One. 2015;10(5):e0128006
• All: 3 reference(s)