Vcan^tm1.1Cwf
Targeted Allele Detail

Summary

• Symbol: Vcan^tm1.1Cwf
• Name: versican; targeted mutation 1.1, Charles W Frevert
• MGI ID: MGI:5824301
• Synonyms: Vcan e4^fl
• Gene: Vcan Location: Chr13:89803431-89890628 bp, - strand Genetic Position: Chr13, 45.5 cM
• Alliance: Vcan^tm1.1Cwf page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:238481
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6NHsd

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: Exon 4 was floxed. Flp-mediated recombination removed the FRT-flanked neomycin resistance cassette inserted downstream of exon 4. (J:238481)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Vcan Mutation: 164 strains or lines available

References

• Original: J:238481 Kang I, et al., Versican Deficiency Significantly Reduces Lung Inflammatory Response Induced by Polyinosine-Polycytidylic Acid Stimulation. J Biol Chem. 2017 Jan 06;292(1):51-63
• All: 3 reference(s)