Tg(Col1a1-PTH1R*H223R)CL2Schp
Transgene Detail
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| Symbol: |
Tg(Col1a1-PTH1R*H223R)CL2Schp |
| Name: |
transgene insertion CL2, Ernestina Schipani |
| MGI ID: |
MGI:5824221 |
| Synonyms: |
Col1a1-caPPR, PPR-tg, PPR*Tg |
| Transgene: |
Tg(Col1a1-PTH1R*H223R)CL2Schp Location: unknown
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| Alliance: |
Tg(Col1a1-PTH1R*H223R)CL2Schp page
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| Transgene Type: |
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Transgenic (Inserted expressed sequence) |
| Mutation: |
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Insertion
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Mutation details: Two transgenic lines (CL1 and CL2) expressing the constitutively active human gene with a H223R mutation, under the control of the 2.3-kb fragment of the mouse 1(I) collagen promoter were established. Founder CL1 was shown by Southern blot analysis to carry only one copy of the transgene, while founder CL2 carried several copies. Only CL2 exhibited mutant phenotype and was studied further.
(J:67276)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Original: |
J:67276 Calvi LM, et al., Activated parathyroid hormone/parathyroid hormone-related protein receptor in osteoblastic cells differentially affects cortical and trabecular bone. J Clin Invest. 2001 Feb;107(3):277-86 |
| All: |
12 reference(s) |
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Analysis Tools
