Tg(KRT14-Dkk4)1Dsch
Transgene Detail

Summary

• Symbol: Tg(KRT14-Dkk4)1Dsch
• Name: transgene insertion 1, David Schlessinger
• MGI ID: MGI:5824108
• Synonyms: K14-Dkk4TG
• Transgene: Tg(KRT14-Dkk4)1Dsch Location: unknown
• Alliance: Tg(KRT14-Dkk4)1Dsch page

Transgene origin

• Strain of Origin: C57BL/6J

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(KRT14-Dkk4)1Dsch expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Dkk4 (MGI:2385299)

• Mutation details: This transgene shows skin-specific expression of mouse Dkk4 under KRT14 promoter control. Sharply elevated expression in the back skin of transgenic mice from E14.5 was detectable by Q-PCR assays, and Western blotting confirmed the increased expression of Dkk4 protein in the soluble fraction of E16.5 transgenic skin extract. No line information was given. (J:238689)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:238689 Cui CY, et al., Dkk4 and Eda regulate distinctive developmental mechanisms for subtypes of mouse hair. PLoS One. 2010 Apr 01;5(4):e10009
• All: 2 reference(s)