Pdcd6ip^tm1.1Adz
Targeted Allele Detail

Summary

• Symbol: Pdcd6ip^tm1.1Adz
• Name: programmed cell death 6 interacting protein; targeted mutation 1.1, Alessandra d'Azzo
• MGI ID: MGI:5823249
• Gene: Pdcd6ip Location: Chr9:113480812-113537327 bp, - strand Genetic Position: Chr9, 64.03 cM, cytoband F2
• Alliance: Pdcd6ip^tm1.1Adz page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:238436
• Parent Cell Line: W9.5/W95 (ES Cell)
• Strain of Origin: 129S1/Sv-Oca2⁺ Tyr⁺ Kitl⁺

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: One loxP site was inserted just upstream of exon 2 and a second loxP site 61 bp into exon 3. An FRT flanked neomycin resistance gene cassette was inserted into intron 1. Flp-mediated recombination removed the neo cassette. (J:238436)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Pdcd6ip Mutation: 40 strains or lines available

References

• Original: J:238436 Campos Y, et al., Alix-mediated assembly of the actomyosin-tight junction polarity complex preserves epithelial polarity and epithelial barrier. Nat Commun. 2016 Jun 23;7:11876
• All: 1 reference(s)