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Spontaneous Allele Detail
Symbol: Nlrp12C57BL/6N
Name: NLR family, pyrin domain containing 12; C57BL/6N
MGI ID: MGI:5818576
Synonyms: Nlrp12B6N
Gene: Nlrp12  Location: Chr7:3218784-3249740 bp, - strand  Genetic Position: Chr7, 1.88 cM
Strain of Origin:  C57BL/6N
Allele Type:    Spontaneous (Not Applicable)
Mutation:    Single point mutation
Mutation detailsA sequence variant is identified in C57BL/6N (C) as compared to C57BL/6J (T) at position 3,222,537 (GRCm38). The polymorphism is located in the C-terminal leucine-rich repeat domain and results in a lysine to arginine change at amino acid residue 1034 (p.K1034R). (J:220417)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Nlrp12 Mutation:  28 strains or lines available
Original:  J:220417 Simon MM, et al., A comparative phenotypic and genomic analysis of C57BL/6J and C57BL/6N mouse strains. Genome Biol. 2013;14(7):R82
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.16
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