Kittm1.1Ccai
Targeted Allele Detail
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Symbol: |
Kittm1.1Ccai |
Name: |
KIT proto-oncogene receptor tyrosine kinase; targeted mutation 1.1, Chen-Leng Cai |
MGI ID: |
MGI:5818515 |
Synonyms: |
c-kitSTOP-H2B-tdTomato |
Gene: |
Kit Location: Chr5:75735647-75817382 bp, + strand Genetic Position: Chr5, 39.55 cM
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Alliance: |
Kittm1.1Ccai page
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Germline Transmission: |
Earliest citation of germline transmission:
J:227907
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Parent Cell Line: |
Not Specified (ES Cell)
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Strain of Origin: |
129
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Allele Type: |
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Targeted (Null/knockout, Reporter) |
Mutation: |
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Insertion
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Mutation details: A LoxP-4XPolyA-LoxP-H2B-tdTomate-FRT-Neo-FRT cassette was targeted to the start codon of kit locus with disruption of endogenous ATG by homologous recombination in ES cells. Flp-mediated recombination removed the neo selection cassette, leaving a single FRT site behind.
(J:227907)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Kit Mutation: |
179 strains or lines available
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Original: |
J:227907 Sultana N, et al., Resident c-kit(+) cells in the heart are not cardiac stem cells. Nat Commun. 2015;6:8701 |
All: |
1 reference(s) |
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