Tnnt2^tm2.2Ccai
Targeted Allele Detail

Summary

• Symbol: Tnnt2^tm2.2Ccai
• Name: troponin T2, cardiac; targeted mutation 2.2, Chen-Leng Cai
• MGI ID: MGI:5818511
• Synonyms: cTnT^H2B-GFP
• Gene: Tnnt2 Location: Chr1:135764092-135779998 bp, + strand Genetic Position: Chr1, 59.32 cM
• Alliance: Tnnt2^tm2.2Ccai page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:227907
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Reporter)
• Mutation: Insertion
• Mutation details: A LoxP-nlacZ-4XPolyA-LoxP-H2B-GFP cassette was targeted to the start codon of Tnnt2 locus, with by homologous recombination in ES cells. Resulting mouse line was crossed with Protamine-Cre mice to remove nlacZ and 4xPloyA stop cassette. (J:227907)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Tnnt2 Mutation: 51 strains or lines available

References

• Original: J:227907 Sultana N, et al., Resident c-kit(+) cells in the heart are not cardiac stem cells. Nat Commun. 2015;6:8701
• All: 1 reference(s)