Tg(tetO-Nras*Q61K)#Lc
Transgene Detail

Summary

• Symbol: Tg(tetO-Nras*Q61K)#Lc
• Name: transgene insertion, Lynda Chin
• MGI ID: MGI:5818045
• Synonyms: TetO-iNRAS^Q61K
• Transgene: Tg(tetO-Nras*Q61K)#Lc Location: unknown
• Alliance: Tg(tetO-Nras*Q61K)#Lc page

Transgene origin

• Strain of Origin: Not Specified

Transgene description

• Transgene Type: Transgenic (Humanized sequence, Inducible, Inserted expressed sequence)
• Inducer: doxycycline/tetracycline
• Mutation: Insertion
• Mutation details: The tetracycline operon drives the inducible expression of a cDNA with nucleotide substitutions that result in the amino acid substitution of lysine for glutamine at position 61 (Q61K). (J:238049)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:238049 Kwong LN, et al., Oncogenic NRAS signaling differentially regulates survival and proliferation in melanoma. Nat Med. 2012 Oct;18(10):1503-10
• All: 3 reference(s)