Syndig1^tm1.1Eld
Targeted Allele Detail

Summary

• Symbol: Syndig1^tm1.1Eld
• Name: synapse differentiation inducing 1; targeted mutation 1.1, Elva Diaz
• MGI ID: MGI:5817792
• Synonyms: SynDIG1^flox
• Gene: Syndig1 Location: Chr2:149672703-149846312 bp, + strand Genetic Position: Chr2, 73.8 cM
• Alliance: Syndig1^tm1.1Eld page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:237765
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: An FRT site flanked neomycin resistance gene cassette and loxP sites flanking exon 4 were inserted. The neo cassette was removed through subsequent flp-mediated recombination, leaving a conditional ready allele with a floxed exon 4. (J:237765)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Syndig1 Mutation: 22 strains or lines available

References

• Original: J:237765 Chenaux G, et al., Loss of SynDIG1 Reduces Excitatory Synapse Maturation But Not Formation In Vivo. eNeuro. 2016 Sep-Oct;3(5):ENEURO.0130-16.2016
• All: 1 reference(s)