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Syndig1tm1.1Eld
Targeted Allele Detail
Nomenclature
Symbol: Syndig1tm1.1Eld
Name: synapse differentiation inducing 1; targeted mutation 1.1, Elva Diaz
MGI ID: MGI:5817792
Synonyms: SynDIG1flox
Gene: Syndig1  Location: Chr2:149830783-150004392 bp, + strand  Genetic Position: Chr2, 73.8 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:237765
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsAn FRT site flanked neomycin resistance gene cassette and loxP sites flanking exon 4 were inserted. The neo cassette was removed through subsequent flp-mediated recombination, leaving a conditional ready allele with a floxed exon 4. (J:237765)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Syndig1 Mutation:  17 strains or lines available
References
Original:  J:237765 Chenaux G, et al., Loss of SynDIG1 Reduces Excitatory Synapse Maturation But Not Formation In Vivo. eNeuro. 2016 Sep-Oct;3(5)
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
08/13/2019
MGI 6.14
The Jackson Laboratory