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Targeted Allele Detail
Symbol: Mir96tm2.2Wtsi
Name: microRNA 96; targeted mutation 2.2, Wellcome Trust Sanger Institute
MGI ID: MGI:5817459
Gene: Mir96  Location: Chr6:30169446-30169551 bp, - strand  Genetic Position: Chr6, 12.52 cM
Germline Transmission:  Earliest citation of germline transmission: J:174268
Parent Cell Line:  JM8A3 (ES Cell)
Strain of Origin:  C57BL/6N-Atm1Brd
Project Collection: IMPC
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
Mutation detailsThe insertion of the PGK_EM7_PuDtk_bGHpA cassette created a deletion of Chromosome 6 (Genome Build 37). This deletion eliminates the DNA sequence for this microRNA. The cassette is composed of a loxP site followed by an F3 site followed by a PGK-puromycin-delta-tk cassette, a loxP site and finally an FRT site. Recombination events removed the selection cassette.
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Mir96 Mutation:  5 strains or lines available
Original:  J:174268 Prosser HM, et al., A resource of vectors and ES cells for targeted deletion of microRNAs in mice. Nat Biotechnol. 2011 Aug 7;29(9):840-5
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.14
The Jackson Laboratory