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Spontaneous Allele Detail
Symbol: Gpr84del
Name: G protein-coupled receptor 84; deletion
MGI ID: MGI:5812913
Gene: Gpr84  Location: Chr15:103216662-103219039 bp, - strand  Genetic Position: Chr15, 58.88 cM
Strain of Origin:  multiple strains
Allele Type:    Spontaneous (Null/knockout)
Mutation:    Intragenic deletion
Mutation detailsThis spontaneously arising frameshift deletion is located in exon 2 at position 103308576 bp (NCBI Build 37) and results in a premature stop codon. The mutation is predicted to result in a truncated protein lacking the transmembrane domains 4-7. The inbred strains BDP/J, DBA/1J, DBA/2J, I/LnJ, FVB/NJ, LG/J, MRL/MpJ, NODShi/LtJ, NOR/LtJ, P/J, PL/J, SKHIN/Sprd, SJL/J, SM/J are homozygous for the deletion. The allele is segregating in the outbred stocks ICR and CD-1. (J:237405)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 15 strains available      Cell Lines: 0 lines available
Carrying any Gpr84 Mutation:  27 strains or lines available
Original:  J:237405 Perez CJ, et al., Several classical mouse inbred strains, including DBA/2, NOD/Lt, FVB/N, and SJL/J, carry a putative loss-of-function allele of Gpr84. J Hered. 2013 Jul-Aug;104(4):565-71
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
MGI 6.20
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