Lmnb1^tm1.1Yxz
Targeted Allele Detail

Summary

• Symbol: Lmnb1^tm1.1Yxz
• Name: lamin B1; targeted mutation 1.1, Yixian Zheng
• MGI ID: MGI:5812122
• Synonyms: LB1d, Lmnb1-, Lmnb1d
• Gene: Lmnb1 Location: Chr18:56840885-56886496 bp, + strand Genetic Position: Chr18, 30.84 cM
• Alliance: Lmnb1^tm1.1Yxz page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:94077
• Parent Cell Line: v6.5 (ES Cell)
• Strain of Origin: (C57BL/6 x 129S4/SvJae)F1

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: The 1.6-kb proximal promoter region and first exon were replaced by a loxP-flanked neomycin resistance cassette. The cassette subsequently was deleted in the germline by Cre recombinase activity. (J:94077, J:178993)
• Inheritance: Recessive

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Lmnb1 Mutation: 38 strains or lines available

References

• Original: J:94077 Mutant Mouse Regional Resource Centers, Information obtained from the Mutant Mouse Regional Resource Centers (MMRRC). Unpublished. 2004-2015
• All: 4 reference(s)