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Acox2tm1(EGFP/cre/ERT2)Wtsi
Targeted Allele Detail
Nomenclature
Symbol: Acox2tm1(EGFP/cre/ERT2)Wtsi
Name: acyl-Coenzyme A oxidase 2, branched chain; targeted mutation 1, Wellcome Trust Sanger Institute
MGI ID: MGI:5811647
Gene: Acox2  Location: Chr14:14210420-14244262 bp, + strand  Genetic Position: Chr14, 4.77 cM, cytoband A1
Mutation
origin
Mutant Cell Line:  CEPD0060_2_E04
Germline Transmission:  Earliest citation of germline transmission: J:204812
Parent Cell Line:  JM8.N4 (ES Cell)
Strain of Origin:  C57BL/6N
Project Collection: EUCOMMTOOLS
Mutation
description
Allele Type:    Targeted (Conditional ready, Inducible, Recombinase, Reporter)
Inducer:    tamoxifen
Mutation:    Insertion
 
Mutation detailsAccording to the allele molecular image presented by the International Knockout Mouse Consortium, this allele has loxP sites flanking exon 6 and 7, and inserted into the intron between exons 5 and 6 is one FRT site, an engrailed 2 splice acceptor sequence, an EGFP and cre/ERT2 expression cassette, and a Rox flanked puromycin resistance cassette. (J:155845)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Acox2     Summary of all recombinase alleles driven by Acox2.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Acox2 Mutation:  26 strains or lines available
References
Original:  J:155845 Wellcome Trust Sanger Institute, Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute. MGI Direct Data Submission. 2010;
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
01/18/2022
MGI 6.17
The Jackson Laboratory