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L3mbtl2tm1.1Haho
Targeted Allele Detail
Nomenclature
Symbol: L3mbtl2tm1.1Haho
Name: L3MBTL2 polycomb repressive complex 1 subunit; targeted mutation 1.1, Hanno Hock
MGI ID: MGI:5810649
Synonyms: FLdeltaN
Gene: L3mbtl2  Location: Chr15:81663889-81688315 bp, + strand  Genetic Position: Chr15, 38.19 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:227373
Parent Cell Line:  v6.5 (ES Cell)
Strain of Origin:  (C57BL/6 x 129S4/SvJae)F1
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsLoxP sites flanking exons 9-14 and a neomycin gene flanked by FRT sites were inserted via homologous recombination. Flp-mediated recombination removed the neomycin gene. (J:227373)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any L3mbtl2 Mutation:  46 strains or lines available
References
Original:  J:227373 Qin J, et al., The polycomb group protein L3mbtl2 assembles an atypical PRC1-family complex that is essential in pluripotent stem cells and early development. Cell Stem Cell. 2012 Sep 7;11(3):319-32
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
07/29/2020
MGI 6.15
The Jackson Laboratory