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Aipl1tvrm119
Chemically induced Allele Detail
Nomenclature
Symbol: Aipl1tvrm119
Name: aryl hydrocarbon receptor-interacting protein-like 1; translational vision research model 119
MGI ID: MGI:5810589
Gene: Aipl1  Location: Chr11:72027963-72037509 bp, - strand  Genetic Position: Chr11, 43.81 cM
Mutation
origin
Strain of Origin:  C57BL/6J
Mutation
description
Allele Type:    Chemically induced (ENU) (Not Specified)
Mutation:    Single point mutation
 
Mutation detailsThis ENU-induced c.276+5G>A single nucleotide transition in a splice donor site is predicted to delete expression of exon 2 and thereby result in an in-frame deletion of amino acids Val33-Ile92, which includes much of the FKBP homology domain. (J:243745)
Inheritance:    Recessive
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Aipl1 Mutation:  12 strains or lines available
References
Original:  J:243745 Krebs MP, et al., Mouse models of human ocular disease for translational research. PLoS One. 2017;12(8):e0183837
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
03/24/2020
MGI 6.15
The Jackson Laboratory