Plxnb2^tm1.1Rkun
Targeted Allele Detail

Summary

• Symbol: Plxnb2^tm1.1Rkun
• Name: plexin B2; targeted mutation 1.1, Rohini Kuner
• MGI ID: MGI:5807117
• Synonyms: Plxnb2^flox
• Gene: Plxnb2 Location: Chr15:89039752-89064960 bp, - strand Genetic Position: Chr15, 44.68 cM, cytoband E3
• Alliance: Plxnb2^tm1.1Rkun page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:221423
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A neo/TK selection cassette flanked by loxP sites was introduced into intron 18 and an additional loxP site was introduced into intron 23. (J:121970)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Plxnb2 Mutation: 87 strains or lines available

References

• Original: J:121970 Deng S, et al., Plexin-B2, but not Plexin-B1, critically modulates neuronal migration and patterning of the developing nervous system in vivo. J Neurosci. 2007 Jun 6;27(23):6333-47
• All: 4 reference(s)