Ifngr1^m1Btlr
Chemically induced Allele Detail

Summary

• Symbol: Ifngr1^m1Btlr
• Name: interferon gamma receptor 1; mutation 1, Bruce Beutler
• MGI ID: MGI:5806453
• Synonyms: marigold
• Gene: Ifngr1 Location: Chr10:19467697-19485977 bp, + strand Genetic Position: Chr10, 8.49 cM
• Alliance: Ifngr1^m1Btlr page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Beutler Mutagenetix

Mutation description

• Allele Type: Chemically induced (ENU) (Not Specified)
• Mutation: Single point mutation
• Mutation details: ENU-induced T to C transition at base pair 19,601,485 (v38) on chromosome 10, or base pair 9,528 in the GenBank genomic region NC_000076 within the donor splice site of intron 3. The effects of the mutation at the cDNA and protein level have not examined, but the mutation could result in skipping of the 164-nucleotide exon 3 (out of 7 total exons). Deletion of exon 3 would result in a frame-shift and coding of 24 aberrant amino acids followed by a premature stop codon after amino acid 100. (J:236694)
• Inheritance: Recessive

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ifngr1 Mutation: 52 strains or lines available

References

• Original: J:236694 Sun L, et al., Mutagenetix entry for marigold. MGI Direct Data Submission. 2016
• All: 1 reference(s)