Oprl1^tm1.1Ltol
Targeted Allele Detail

Summary

• Symbol: Oprl1^tm1.1Ltol
• Name: opioid receptor-like 1; targeted mutation 1.1, Lawrence Toll
• MGI ID: MGI:5805977
• Synonyms: NOP^eGFP
• Gene: Oprl1 Location: Chr2:181356809-181362778 bp, + strand Genetic Position: Chr2, 103.74 cM, cytoband H2-4
• Alliance: Oprl1^tm1.1Ltol page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:226096
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A floxed neomycin resistant gene was inserted upstream of exon 4 and the stop codon in exon 5 was replaced by a Gly-Ser-Ile-Ala-Thr-eGFP encoding cDNA followed by a stop codon. Cre-mediated recombination removed the selection cassette. (J:226096)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Oprl1 Mutation: 28 strains or lines available

References

• Original: J:226096 Ozawa A, et al., Knock-In Mice with NOP-eGFP Receptors Identify Receptor Cellular and Regional Localization. J Neurosci. 2015 Aug 19;35(33):11682-93
• All: 3 reference(s)