Npy1r^{tm1.1(cre/GFP)Rpa}
Targeted Allele Detail

Summary

• Symbol: Npy1r^{tm1.1(cre/GFP)Rpa}
• Name: neuropeptide Y receptor Y1; targeted mutation 1.1, Richard D Palmiter
• MGI ID: MGI:5804208
• Synonyms: Npy1r^cre:GFP
• Gene: Npy1r Location: Chr8:67149844-67159444 bp, + strand Genetic Position: Chr8, 33.15 cM, cytoband B3-C2
• Alliance: Npy1r^{tm1.1(cre/GFP)Rpa} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:234810
• Parent Cell Line: G4 (ES Cell)
• Strain of Origin: (129S6/SvEvTac x C57BL/6NCrl)F1

Mutation description

• Allele Type: Targeted (Recombinase, Reporter)
• Mutation: Insertion
• Npy1r^{tm1.1(cre/GFP)Rpa} expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Npy1r (MGI:104963)

• Mutation details: A cre/GFP fusion gene with a neo cassette was inserted just 5' fo the normal initiation codon for Npy1r gene. The neo cassette was then removed by action of FLP recombinase. (J:234810)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Npy1r (mouse) Summary of all recombinase alleles driven by Npy1r. Comparative matrix view of recombinase activities Alliance mouse Npy1r gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Npy1r Mutation: 25 strains or lines available

References

• Original: J:234810 Padilla SL, et al., Agouti-related peptide neural circuits mediate adaptive behaviors in the starved state. Nat Neurosci. 2016 May;19(5):734-41
• All: 6 reference(s)