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Npy1rtm1.1(cre/GFP)Rpa
Targeted Allele Detail
Nomenclature
Symbol: Npy1rtm1.1(cre/GFP)Rpa
Name: neuropeptide Y receptor Y1; targeted mutation 1.1, Richard D Palmiter
MGI ID: MGI:5804208
Synonyms: Npy1rcre:GFP
Gene: Npy1r  Location: Chr8:66697192-66706792 bp, + strand  Genetic Position: Chr8, 33.15 cM, cytoband B3-C2
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:234810
Parent Cell Line:  G4 (ES Cell)
Strain of Origin:  (129S6/SvEvTac x C57BL/6NCrl)F1
Mutation
description
Allele Type:    Targeted (Recombinase, Reporter)
Mutation:    Insertion
 
Mutation detailsA cre/GFP fusion gene with a neo cassette was inserted just 5' fo the normal initiation codon for Npy1r gene. The neo cassette was then removed by action of FLP recombinase. (J:234810)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Npy1r     Summary of all recombinase alleles driven by Npy1r. Comparative matrix view of recombinase activities
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Npy1r Mutation:  14 strains or lines available
References
Original:  J:234810 Padilla SL, et al., Agouti-related peptide neural circuits mediate adaptive behaviors in the starved state. Nat Neurosci. 2016 May;19(5):734-41
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
08/04/2020
MGI 6.15
The Jackson Laboratory