Tg(KRT14-TCL1A)1Rso
Transgene Detail

Summary

• Symbol: Tg(KRT14-TCL1A)1Rso
• Name: transgene insertion 1, Giandomenico Russo
• MGI ID: MGI:5804015
• Synonyms: K14-hTCL1, K14-TCL1
• Transgene: Tg(KRT14-TCL1A)1Rso Location: unknown
• Alliance: Tg(KRT14-TCL1A)1Rso page

Transgene origin

• Strain of Origin: C57BL/6NCrl

Transgene description

• Transgene Type: Transgenic (Humanized sequence, Inserted expressed sequence)
• Mutation: Insertion
• Tg(KRT14-TCL1A)1Rso expresses 1 gene
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  TCL1A (8115)

  Tcl1	(MGI:1097166)

• Mutation details: The transgene construct comprises the pG3Z-K14 expression vector into which a cDNA encoding human T-cell leukemia/lympoma 1A (TCL1A) has been inserted at the unique BamHI restriction endonuclease recognition site downstream of the beta-globin intron. The expression cassette contains the promoter and polyadenylation signal of the human keratin 14 gene (KRT14). (J:157374)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:157374 Ragone G, et al., The Tcl1 oncogene defines secondary hair germ cells differentiation at catagen-telogen transition and affects stem-cell marker CD34 expression. Oncogene. 2009 Mar 12;28(10):1329-38
• All: 2 reference(s)