Tg(Gfap-PTEN*)6Rpm
Transgene Detail

Summary

• Symbol: Tg(Gfap-PTEN*)6Rpm
• Name: transgene insertion 6, Rafael Pulido
• MGI ID: MGI:5795663
• Synonyms: GL1 GFAP-Pten qma, PTEN QMA
• Transgene: Tg(Gfap-PTEN*)6Rpm Location: unknown
• Alliance: Tg(Gfap-PTEN*)6Rpm page

Transgene origin

• Strain of Origin: Not Specified

Transgene description

• Transgene Type: Transgenic (Humanized sequence, Inserted expressed sequence)
• Mutation: Insertion
• Tg(Gfap-PTEN*)6Rpm expresses 1 gene
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  PTEN (5728)

  Pten	(MGI:109583)

• Mutation details: This transgene contains the promoter of the glial fibrillary acidic protein (Gfap) gene directing expression of a full-length human phosphatase and tensin homolog (PTEN) cDNA that has been modified to substitute an alanine codon for that encoding each of the five amino acids in the C-terminal tail that are phosphorylated by casein kinase 2 (CK2): serine 370, serine 380, threonine 382, threonine 383, and serine 385 (S370A/S380A/T382A/T383A/S385A; PTEN QMA). (J:82809, J:234161, J:234163)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:82809 European Mouse Mutant Archive, Information obtained from the European Mouse Mutant Archive (EMMA). Unpublished. 2003-2013
• All: 3 reference(s)