Stat3^tm1.1Vpo
Targeted Allele Detail

Summary

• Symbol: Stat3^tm1.1Vpo
• Name: signal transducer and activator of transcription 3; targeted mutation 1.1, Valeria Poli
• MGI ID: MGI:5793045
• Gene: Stat3 Location: Chr11:100777632-100830447 bp, - strand Genetic Position: Chr11, 63.82 cM
• Alliance: Stat3^tm1.1Vpo page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:232020
• Parent Cell Line: E14 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exons 12 through 14 were flanked by intronic loxP sites. Cre-mediated recombination removed exons 12 through 14 and the selection cassette. (J:232020)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Stat3 Mutation: 72 strains or lines available

References

• Original: J:232020 Ermakova O, et al., Sensitized phenotypic screening identifies gene dosage sensitive region on chromosome 11 that predisposes to disease in mice. EMBO Mol Med. 2011 Jan;3(1):50-66
• All: 1 reference(s)