Chd5^{tm1b(EUCOMM)Wtsi}
Targeted Allele Detail

Summary

• Symbol: Chd5^{tm1b(EUCOMM)Wtsi}
• Name: chromodomain helicase DNA binding protein 5; targeted mutation 1b, Wellcome Trust Sanger Institute
• MGI ID: MGI:5792826
• Synonyms: Chd5^Tm1b
• Gene: Chd5 Location: Chr4:152423108-152474651 bp, + strand Genetic Position: Chr4, 83.04 cM, cytoband E2
• Alliance: Chd5^{tm1b(EUCOMM)Wtsi} page
• IMPC: Chd5 gene page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:224506
• Parent Cell Line: JM8A3.N1 (ES Cell)
• Strain of Origin: C57BL/6N-A^tm1Brd
• Project Collection: EUCOMM

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: The L1L2_Bact_P cassette was inserted at position 152431946 of Chromosome 4 upstream of exon 2 (Build GRCm39). The cassette is composed of an FRT site followed by lacZ sequence. Exon 2 was deleted by cre-mediated recombination of loxP sites flanking the critical exon. (J:224506)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Chd5 Mutation: 73 strains or lines available

References

• Original: J:224506 Li W, et al., Chd5 orchestrates chromatin remodelling during sperm development. Nat Commun. 2014;5:3812
• All: 2 reference(s)