Gje1^{tm1c(EUCOMM)Hmgu}
Targeted Allele Detail

Summary

• Symbol: Gje1^{tm1c(EUCOMM)Hmgu}
• Name: gap junction protein, epsilon 1; targeted mutation 1c, Helmholtz Zentrum Muenchen GmbH
• MGI ID: MGI:5792169
• Gene: Gje1 Location: Chr10:14591367-14593958 bp, - strand Genetic Position: Chr10, 5.5 cM, cytoband A2
• Alliance: Gje1^{tm1c(EUCOMM)Hmgu} page
• IMPC: Gje1 gene page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:157065
• Parent Cell Line: JM8A3.N1 (ES Cell)
• Strain of Origin: C57BL/6N-A^tm1Brd
• Project Collection: EUCOMM

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: Flp-mediated excision of the parental Gje1^{m1a(EUCOMM)Wtsi} allele resulted in the removal of the promoter-driven neomycin selection cassette and the inserted lacZ reporter sequence, leaving behind the loxP-flanked critical exon(s). Further information on targeting strategies used for this and other IKMC alleles can be found at http://www.informatics.jax.org/mgihome/nomen/IKMC_schematics.shtml. (J:157065)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Gje1 Mutation: 22 strains or lines available

References

• Original: J:157065 Helmholtz Zentrum Muenchen GmbH, Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu). MGI Direct Data Submission. 2010-2015
• All: 1 reference(s)