Idh3a^mpc201H
Chemically induced Allele Detail

Summary

• Symbol: Idh3a^mpc201H
• Name: isocitrate dehydrogenase 3 (NAD+) alpha; muta-ped-c3pde 201, Harwell
• MGI ID: MGI:5792025
• Synonyms: Idh3a^E229K
• Gene: Idh3a Location: Chr9:54493795-54511946 bp, + strand Genetic Position: Chr9, 29.7 cM
• Alliance: Idh3a^mpc201H page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Harwell ENU Mutagenesis

Mutation description

• Allele Type: Chemically induced (ENU) (Not Specified)
• Mutation: Single point mutation
• Mutation details: ENU mutagenesis induced a G to A point mutation that results in the amino acid substitution of glutamic acid with lysine at position 229 (p.E229K). (J:234901)
• Inheritance: Recessive

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Idh3a Mutation: 21 strains or lines available

References

• Original: J:234901 Potter PK, et al., Novel gene function revealed by mouse mutagenesis screens for models of age-related disease. Nat Commun. 2016;7:12444
• All: 3 reference(s)