Lyst^bg-8Btlr
Chemically induced Allele Detail

Summary

• Symbol: Lyst^bg-8Btlr
• Name: lysosomal trafficking regulator; beige 8 Bruce Beutler
• MGI ID: MGI:5789550
• Synonyms: vulpix
• Gene: Lyst Location: Chr13:13764982-13953388 bp, + strand Genetic Position: Chr13, 5.28 cM
• Alliance: Lyst^bg-8Btlr page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Beutler Mutagenetix

Mutation description

• Allele Type: Chemically induced (ENU) (Not Specified)
• Mutation: Single point mutation
• Mutation details: ENU-induced T to C transition at base pair 13,696,794 (v38) on chromosome 13, or base pair 106,456 in the GenBank genomic region NC_000079 for the Lyst gene. The effect of the mutation at the cDNA and protein level have not examined, but the mutation is predicted to result in skipping of the 179-nucleotide exon 30 (out of 53 total exons), resulting in an in-frame deletion of 59 amino acids after amino acid 2,643 of the protein. (J:234242)
• Inheritance: Recessive

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Lyst Mutation: 225 strains or lines available

References

• Original: J:234242 Reyna C, et al., Mutagenetix entry for vulpix. MGI Direct Data Submission. 2016
• All: 1 reference(s)