Cxcl12^tm1.2Mjok
Targeted Allele Detail

Summary

• Symbol: Cxcl12^tm1.2Mjok
• Name: C-X-C motif chemokine ligand 12; targeted mutation 1.2, Milan Joksimovic
• MGI ID: MGI:5788866
• Synonyms: CXCL12^deltaex2
• Gene: Cxcl12 Location: Chr6:117145496-117158328 bp, + strand Genetic Position: Chr6, 54.81 cM, cytoband F1
• Alliance: Cxcl12^tm1.2Mjok page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:226611
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A loxP site was inserted upstream of exon 2 and a loxP/FRT flanked neo cassette was inserted downstream of exon 2 via homologous recombination. Recombinase mediated recombination removed the neo cassette and exon 2. (J:226611)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Cxcl12 Mutation: 24 strains or lines available

References

• Original: J:226611 Hillmer RE, et al., Generation and characterization of mice harboring a conditional CXCL12 allele. Int J Dev Biol. 2015;59(4-6):205-9
• All: 1 reference(s)